Carolina Larraín

Carolina Larraín

Carolina Larraín

Tema principal: Quimiorreceptores carotídeos y regulación refleja ventilatoria y cardiovascular

  • Enfermera, Cruz Roja Chilena, 1963.
  • Certificate of Proficiency in English, Univ Cambridge, UK, 1993.
  • Traductora, Instituto Chileno.Británico, 2002.
  • Adiestramiento en investigación, Dept Physiology, Univ Utah, USA, 1981-1982.
  • Colaboración en investigación, Laboratorio Neurobiología, Pontificia Universidad Católica Chile, 1977-2003.
  • Coordinación docente y pasos prácticos, Curso Fisiología General y Neurofisiología, Pontificia Universidad Católica Chile, 1982-2002.
  • Docente Fisiología, Fac Medicina, CAS-Univ Desarrollo, Chile, 2004.

 

Publicaciones

 

  • 1978 Zapata P , Larraín C. Antagonism of dopamine induced chemosensory inhibition by ergot alkaloids. Neurosci Lett 8: 131 136
  • 1989 Eugenín J, Larraín C, Zapata P. Correlative contribution of carotid and aortic afferences to the ventilatory chemosensory drive in steady state normoxia and to the ventilatory chemoreflexes induced by transient hypoxia. Arch Biol Med Exp 22: 395 408
  • 1990 Eugenín J, Larraín C, Zapata P. Functional recovery of the ventilatory chemoreflexes after partial chronic denervation of the nucleus tractus solitarius. Brain Res 523: 263 272
  • 1990 Zapata P, Eugenín J, Larraín C. Plasticity of ventilatory chemoreflexes. Chapter 49 in: Eyzaguirre C, Fidonde SJ, Firzgerald RS, Lahiri S, McDonald DM (eds) Arterial Chemoreception. NY: Springer Verlag. pp 357 362
  • 1990 Zapata P, Larraín C, Eugenín J. Restoration of chemoreflexes after unilateral carotid deafferentation. In: ACKER H, TRZEBSKI A, O’REGAN RG (eds) Chemoreceptors and Chemoreceptor Reflexes. NY: Plenum. pp 339 346
  • 1991 Oyarzun MJ, Iturriaga R, Donoso P, Dussaubat N, Santos M, Schiappacasse ME, LathroP ME, Larraín C, Zapata P. Factors affecting the distribution of alveolar surfactant during resting ventilation. Am J Physiol 261 (Lung Cel Molec Physiol 5): L210 L217
  • 1991 Fadic R, Larraín C, Zapata P. Thermal effects on ventilation in cats. Participation of carotid body chemoreceptors. Respir Physiol 86: 51 63
  • 1991 Loyola H, Fadic R, Cárdenas H, Larraín C, Zapata P. Effects of body temperature on chemosensory activity of the cat carotid body in situ. Neurosci Lett 132: 251 254
  • 1992 Oyarzun MJ, Morgado E, Dussaubat N, Lathrop ME, Iturriaga R, Larraín C, Zapata P. Comparison of the subcellular distribution of alveolar surfactant in two mammalian species of similar body weight: cat and rabbit. Comp Biochem Physiol 102: 669 674
  • 1993 Zapata P, Larraín C, Fadic R, Ramirez B, Loyola H. Thermal effects upon the chemosensory drive of ventilation. Chapter 52 in: DATA PG, ACKER H, LAHIRI S (eds) Neurobiology and Cell Physiology of Chemoreception. NY: Plenum. Adv Exp Med Biol 337: 371-378
  • 1994 Iturriaga R, Larraín C, Zapata P. Phrenic nerve activity during artificial ventilation at different body temperatures and its relationships with carotid chemosensory activity. Biol Res 27: 145-157
  • 1994 Zapata P, Larraín C, Iturriaga R, Alcayaga J. The carotid bodies as thermosensors: experiments in vitro and in situ, and importance for ventilatory regulation. In: O’Regan RG, NOLAN P, McQueen DS, Paterson DJ (eds) Arterial Chemoreception: Cell to System. NY: Plenum. Adv Exp Med Biol 360: 253-255
  • 1994 Iturriaga R, Larraín C, Zapata P. Effects of dopaminergic blockade upon carotid chemosensory activity and its hypoxia-induced excitation. Brain Res 663: 145-154
  • 1994 Zapata P, Larraín C. A report on the evolution of this journal and an analysis of its present state and perspectives. Biol Res 27: 159-169
  • 1995 Zapata P, Larraín C. Development of a Latin American biological journal. Chapter VII in: CETTO AM, HILLERUD K-I (eds) Scientific Publications in Latin America. México: Fondo Cultura Económica. pp 89-102 [In Spanish]
  • 1996 Zapata P, Iturriaga R, Larraín C. Domperidone as a tool to assess the role of dopamine within carotid body chemoreception. Chapter 44 in: ZAPATA P, EYZAGUIRRE C, TORRANCE RW (eds) Frontiers in Arterial Chemoreception. London & New York: Plenum. Adv Exp Med Biol 410: 291-297
  • 2000 Zapata P, Larraín C. Reminiscence of Bob Torrance. Adv Exp Biol Med 475: 7-8
  • 2000 Zapata P, Larraín C, Iturriaga R, Alcayaga J, Eyzaguirre C. Interactions between acetylcholine and dopamine in chemoreception. Adv Exp Med Biol 475: 495-506
  • 2002 Zapata P, Larraín C, Fernández R. Nicotine-evoked ventilatory reflexes in cats: sites of origin and afferences. J Anat 200: 204
  • 2002 Fernández R, Larraín C, Zapata P. Acute ventilatory and circulatory reactions evoked by nicotine: are they excitatory or depressant? Respir Physiol Neurobiol 133: 173-182
  • 2003 Zapata P, Larraín C, Fernández R, Reyes EP: Cholinergic actions on carotid chemosensory system. Adv Exp Med Biol 536: 277-283
  • 2003 Fernández R, Arriagada Y, Garrido AM, Larraín C, Zapata P: Ventilatory chemosensory drive in cats, rats and Guinea-pigs. Adv Exp Med Biol 536: 489- 495
  • 2005 Reyes EP, Fernández R, Larraín C, Zapata P. Effect of combined cholinergic-purinergic block on carotid body chemosensory activity in situ. J Physiol, Lond 565P: PC169
  • 2005 Zapata P, Fernández R, Reyes EP, Larraín C. Acute inflammation of the carotid body: functional manifestations. J Physiol, Lond 565P: C169
  • 2005 Zapata P, Larrain C. How the carotid body works: Different strategies and preparations to solve different problems. Biol Res 38: 315-328
  • 2007 Reyes EP, Fernández R, Larraín C, Zapata P. Effects of combined cholinergic-purinergic block upon cat carotid body chemoreceptors in vitro. Respir Physiol Neurobiol 156: 17-22
  • 2007 Reyes EP, Fernández R, Larraín C, Zapata P. Carotid body chemosensory activity and ventilatory chemoreflexes in cats persist after combined cholinergic–purinergic block. Respir Physiol Neurobiol 156: 23-32
  • 2008 Fernández R, González S, Rey S, Cortés PP, Maisey KR, Reyes EP, Larraín C, Zapata P. Lipopolysaccharide-induced carotid body inflammation in cats: Functional manifestations,  histopathology and involvement of tumour necrosis factor-. Exp Physiol 93: 892-907
  • 2009 Zapata P, Larraín C, Rivera MA, Calderón C. Cardio-vascular responses to hyperoxic withdrawal of arterial chemosensory drive. Adv Exp Med Biol 648: 305-314
  • 2011 Zapata P, Larraín C, Reyes P, Fernández R. Immunosensory signaling by carotid body chemoreceptors. Respir Physiol Neurobiol 178: 370-374
  • 2012 Zapata P, Larraín C, Reyes P, Fernández R. Shifting from hypoxia to hyperoxia to assess the peripheral chemosensory drive of ventilation. Adv Exp Med Biol, 758: 137-142