Publicaciones científicas


Fernando Ezquer, Paola Morales, María Elena Quintanilla, Daniela Santapau, Carolyne Lespay-Rebolledo, Marcelo Ezquer, Mario Herrera-Marschitz & Yedy Israel. Intravenous administration of anti-inflammatory mesenchymal stem cell spheroids reduces chronic alcohol intake and abolishes bingedrinkingScientific Reports (2018) 8:4325 | DOI:10.1038/s41598-018-22750-7


Rojo, D.; Conget, PCell-free derivatite from mesenchymal stem cells prevents peritoneal adhesions formation. Cytotherapy. 2016 Jun.

Maximiliano Giraud-Billoud M, Ezquer F, Bahamonde J, Ezquer M. Tubulointerstitial injury and proximal tubule albumin transport in early diabetic nephropathy induced by type 1 diabetes mellitus. Biological Research. 2016.

Amaya C., Militello R.D., Calligaris S.D., Colombo M.I. Rab24 interacts with the Rab7/Rab interacting lysosomal protein complex to regulate endosomal degradation. Traffic. 2016 Nov: 1181-1196. Doi: 10.1111/tra.12431

Tekin N., Omidvar N., Morris T.P., Conget P., Bruna F., Timar B., Gagyi E., Basak R., Naik O., Auewarakul C., Sritana N., Levy D., Cerci J.J., Bydlowski S.P., Pereira J., Dimamay M.P., Natividad F., Chung J.-K., Belder N., Kuzu I., Paez D., Dondi M., Carr R., Ozdag H., Padua R.A. Protocol for qRT-PCR analysis from formalin fixed paraffin embedded tissue sections from diffuse large b-cell lymphoma: Validation of the six-gene predictor score. Oncotarget. 2016 Nov. Doi: 10.18632/oncotarget.13066

Araos J., Alegría L., García P., Damiani F., Tapia P., Soto D., Salomon T., Rodriguez F., Amthauer M., Erranz B., Castro G., Carreño P., Medina T., Retamal J., Cruces P., Bugedo G., Bruhn A. Extracorporeal membrane oxygenation improves survival in a novel 24-hour pig model of severe acute respiratory distress syndrome. American Journal of Translation Research. 2016.

Losinno A.D., Sorrivas V., Ezquer M., Ezquer F., López L.A., Morales A. Changes of myoid and endothelial cells in the peritubular wall during contraction of the seminiferous tubule. Cell and Tussue Research .2016 Ago: 425-435. Doi: 10.1007/s00441-016-2386-x

Bruna F., Contador D., Conget P., Erranz B., Sossa C.L., Arango-Rodríguez M.L. Regenerative Potential of Mesenchymal Stromal Cells: Age-Related Changes. Stem Cells International . 2016. Doi: 10.1155/2016/1461648

Robert Carr, Hilal Ozdag, Nilgun Tekin, Timothy Morris, Paulette Conget, Flavia Bruna, Botond Timar, Eva Gagyi, Ranjan Basak, Omkar Naik, Chirayu, Auewarakul, Narongrit Srithana, Mark Pierre Dimamay, Filipinas Natividad, June-Key Chung, Nevin Belder, Isinsu Kuzu, Nader Omidvar, Diana Paez & Rose Ann Padua. The effect of biological heterogeneity on RCHOP treatment outcome in diffuse large B-cell lymphoma across five international regions. Leukemia & Lymphoma. 2016 Oct. Doi: 10.1080/10428194.2016.1231308

Ezquer F., Bruna F., Calligaris S., Conget P., Ezquer MMultipotent mesenchymal stromal cells: A promising strategy to manage alcoholic liver disease. World Journal of Gastroenterology. 2016 Ene: 24-36. Doi: 10.3748/wjg.v22.i1.24

Soledad Vera, Luz Maria Pozo, René Lopez, Joaquin Diaz and Paulette Conget. The Plasma is a Suitable Sample for Moderate Magnesium Deficiency Assessment but the Poor Accuracy of Colorimetric Technique Limits its Use. Annals of Clinical and Laboratory Research. 2016 May.

Ezquer M., Urzua C.A., Montecino S., Leal K., Conget P., Ezquer FIntravitreal administration of multipotent mesenchymal stromal cells triggers a cytoprotective microenvironment in the retina of diabetic mice. Stem Cell Res Ther. 2016. Doi  10.1186/s13287-016-0299-y

Tekin, N.; Omidvar, N.; Morris, T.; Timar, B.; Gagyi, E.; Conget, P.; Bruna, F.; Basak, R.; Naik, O.; Auewarakul, C. Udomsakdi; Sritana, N.; Levy, D.; Bydlowski, S. P.; Pereira, J.; Dimamay, M. P.; Natividad, F.; Chung, J. K.; Belder, N.; Kuzu, I.; Paez, D.; Dondi, M.; Carr, R.; Ozdag, H.; Padua, R. A. Diffuse large b-cell lymphoma (dlbcl) study reveals biological heterogeneity between ethnically diverse countries; validation of 6-gene prognostic score in an international cohort. Haematologica. 2016.

Fernando E. Ezquer, Marcelo E. Ezquer, Jose M. Vicencio & Sebastián D. Calligaris. Two complementary strategies to improve cell engraftment in mesenchymal stem cell-based therapy: increasing transplanted cell resistance and increasing tissue receptivity. Cell Adhesion & Migration. 2016. Doi 10.1080/19336918.2016.1197480

Abrigo J., Rivera J.C., Aravena J., Cabrera D., Simon F., Ezquer F., Ezquer M., Cabello-Verrugio C. High Fat Diet-Induced Skeletal Muscle Wasting Is Decreased by Mesenchymal Stem Cells Administration: Implications on Oxidative Stress, Ubiquitin Proteasome Pathway Activation, and Myonuclear Apoptosis. Cell Adhesion & Migration. 2016. doi: 10.1080/19336918.2016.1197480

Israel Y, Ezquer F, Quintanilla ME, Morales P, Ezquer M, Herrera-Marschitz M. Intracerebral Stem Cell Administration Inhibits Relapse-like Alcohol Drinking in Rats. Alcohol and Alcoholism. 2016. Doi: 10.1093/alcalc/agw068


Diaz F, Erranz B, Donoso A, Salomon T, Cruces P. Influence of tidal volume on pulse pressure variation and stroke volume variation during experimental intra-abdominal hypertension. BMC Anesthesiology. 2015 Sep:22;15.

Ezquer F, Gatica M, Arredondo V, Giraud-Billoud M, Conget P, Ezquer M. Mesenchymal Stem cells prevented the progression of diabetic nephropathy, improved renal function and microvascular architecture in a chronic model of type 1 diabetes mellitus. Cytotherapy. 2015 Jun;17(6):S66-S.

Montecino S, Leal K, Urzua C, Ezquer M, Conget P, Ezquer F. Intravitreal administration of multipotent mesenchymal stromal cells increases neurotrophic factors levels, reduces oxidative damage and prevents retinal neuronal cell loss in diabetic mice. Cytotherapy. 2015 Jun;17(6):S66-S7

Solarte VA, Rosas JE, Rivera ZJ, Arango-Rodriguez ML, Garcia JE, Vernot J-P. A tetrameric peptide derived from bovine lactoferricin exhibits specific cytotoxic effects against oral squamous-cell carcinoma cell lines. Biomed Research International. 2015.

Could cancer and infection be adverse effects of mesenchymal stromal cell therapy? Arango-Rodriguez ML, Ezquer F, Ezquer M, Conget P. World J Stem Cells. 2015 Mar 26;7(2):408-417. Review. PMID:25815124

Ezquer F, Gutiérrez J, Ezquer M, Caglevic C, Salgado HC, Calligaris SD. Mesenchymal stem cell therapy fordoxorubicin cardiomyopathy: hopes and fears. Stem Cell Res Ther. 2015; 6:116.

Contador D, Ezquer F, Espinosa M, Arango-Rodriguez M, Puebla C, Sobrevia L, Conget PDexamethasone and rosiglitazone are sufficient and necessary for producing functional adipocytes from mesenchymal stem cells. Exp Biol Med (Maywood). 2015 Jan 16. pii:1535370214566565. [Epub ahead of print] PMID:25595190[PubMed – as supplied by publisher]

Erranz B, Wilhelm J, Riquelme R, Cruces P. Predisposición genética y síndrome de distrés respiratorio agudo pediátrico: nuevas herramientas de estudio genético. Rev Chil Pediatr. 2015; 86(2):73-79.

Ezquer F, Giraud-Billoud M, Carpio D, Cabezas F, Conget P, Ezquer M. Proregenerative Microenvironment Triggered by Donor Mesenchymal Stem Cells Preserves Renal Function and Structure in Mice with Severe Diabetes Mellitus. Biomed Res Int. 2015. DOI: 10.1155/2015/164703

Campero M, Ezquer M, Ezquer FNerve Excitability and Structural Changes in Myelinated Axons from Diabetic Mice. Exp Clin Endocrinol Diabetes. 2015 Aug 18. [Epub ahead of print] PMID:26285066


Castillo-Rodriguez RA, Arango-Rodriguez ML, Escobedo L, Hernandez-Baltazar D, Gompel A, Forgez P, et al. Suicide HSVtk Gene Delivery by Neurotensin-Polyplex Nanoparticles via the Bloodstream and GCV Treatment Specifically Inhibit the Growth of Human MDA-MB-231 Triple Negative Breast Cancer Tumors Xenografted in Athymic Mice. Plos One. 2014;9(5).

Ezquer ME, Valdez SR, Seltzer AM, Jahn GA. Reversion by vitamin E treatment of the oxidative damage but not of the advancement in reproductive senescence produced by neonatal hypoxia or hypoxia-ischemia in female rats. Neuroendocrinology. 2014;99(3-4):204-18.

Ezquer F, Ezquer M, Arango-Rodriguez M, Conget P. Could donor multipotent mesenchymal stromal cells prevent or delay the onset of diabetic retinopathy? Acta Ophthalmologica. 2014;92(2):E86-E95.

Figueroa D, Espinosa M, Calvo R, Scheu M, Vaisman A, Gallegos M, et al. Anterior cruciate ligament regeneration using mesenchymal stem cells and collagen type I scaffold in a rabbit model. Knee Surgery Sports Traumatology Arthroscopy. 2014;22(5):1196-202.

Figueroa D, Espinosa M, Calvo R, et al. Tratamiento de lesiones condrales agudas de espesorcompleto con ácido hialurónico de alto pesomolecular; un modelo experimental. Revista Española de Cirugía Ortopédica y Traumatología. 2014.

Hernandez ME, Rembao JD, Hernandez-Baltazar D, Castillo-Rodriguez RA, Tellez-Lopez VM, Arango-Rodríguez ML, et al. Safety of the intravenous administration of neurotensin-polyplex nanoparticles in BALB/c mice. Nanomedicine-Nanotechnology Biology and Medicine. 2014;10(4):745-54.

Vaisman A, Montenegro IEV, De Diego MJT, Ronco JV. A Novel Radiographic Index for the Diagnosis of Posterior Acromioclavicular Joint Dislocations. American Journal of Sports Medicine. 2014;42(1):112-6.

Wenzel C, Bruna F, Conget P, Lecannelier J, Descouvieres C, Sandoval C, et al. Mesenchymal stem cells contribute to structutral and morphological recuperation of prolapsed anterior vaginal wall: in vitro study. Neurourology and Urodynamics. 2014 Aug;33(6):894-5.


Calligaris SD, Lecanda M, Solis F, Ezquer M, Gutierrez J, Brandan E, Leiva A, et al. Mice Long-Term High-Fat Diet Feeding Recapitulates Human Cardiovascular Alterations: An Animal Model to Study the Early Phases of Diabetic Cardiomyopathy.  Plos One. 2013; 8(4):e60931.

Calligaris SD, Conget P. Intravenous administration of bone marrow-derived multipotentmesenchymal stromal cells has a neutral effect on obesity-induced diabetic cardiomyopathy. Biological Research. 2013; 46(3):251-255.

Calligaris SD, Ricca M, Conget P. Cardiac stress test induced by dobutamine and monitored by cardiac catheterization in mice. Journal of Visualized Experiments. 2013; (72).

Cruces P, Erranz B, Donoso A, Carvajal C, Salomon T, Torres M, Diaz F. Mild hypothermia increases pulmonary anti-inflammatory response during protective mechanical ventilation in a piglet model of acute lung injury. Pediatric Anesthesia. 2013; 23(11): 1069-1077.

Diaz F, Erranz B, Donoso A, Carvajal C, Salomon T, Torres M, Cruces P. Surfactant deactivation in a pediatric model induces hypovolemia and fluid shift to the extravascular lung compartment. Pediatric Anesthesia. 2013; 23(3):250-257.

Ezquer F, Ezquer M, Arango-Rodriguez M, Conget P. Could donor ultipotent mesenchymal stromal cells prevent or delay the onset of diabetic retinopathy?  Acta Ophthalmologica.2013. doi: 10.1111/aos.12113.

Figueroa D, Calvo R, Villalón I, Tuca MJ, Vaisman A, Valdés M. Clinical factors and findings in knee arthroscopy of patients with knee arthrosis candidates for conversion to total replacement. Revista Española de Cirugía OrtopédicayTraumatolgía. 2013; 57(4):263-267.

Figueroa D, Espinosa M, Calvo R, Scheu M, Vaisman A, Gallegos M, Conget P. Anterior cruciate ligament regeneration using mesenchymal stem cells and collagen type I scaffold in a rabbit model. Knee Surgery Sports Traumatology, Arthroscopy. 2013. doi 10.1007/s00167-013-2471-6

Espinosa M, Vaisman A, Nazal N, Figueroa D, Gallegos M and Conget P (2013) Intraarticular administration of dexamethasone after mesenchymal stem cells implantation does not improve significatively the treatment of pre-established full-thickness chondral defect in a rabbit model. Cartilage doi: 10.1177/1947603512472696

Lazcano X, SantaCruz J and Conget P Teorías implícitas sobre la enseñanza y su asociación con las prácticas pedagógicas de los docentes de la Carrera de Medicina. Rev Educ Cienc Salud (2013)  10:47-52

Espinosa M, Vaisman A, Nazal N, Figueroa D, Gallegos M and Conget P Intraarticular administration of dexamethasone after mesenchymal stem cells implantation does not improve significatively the treatment of pre-established full-thickness chondral defect in a rabbit model. Cartilage (2013) doi: 10.1177/1947603512472696

Pablo A. Vial; Francisca Valdivieso; Marcela Ferres; Raul Riquelme; M. Luisa Rioseco; Mario Calvo; Constanza Castillo; Ricardo Diaz; Luis Scholz; Analia Cuiza; Edith Belmar; Carla Hernandez; Jessica Martinez; Sang-Joon Lee; Gregory J. Mertz; for the Hantavirus Study Group in Chile. High-Dose Intravenous Methylprednisolone for Hantavirus Cardiopulmonary Syndrome in Chile: A Double-Blind, Randomized Controlled Clinical Trial. Clinical Infectious Diseases 2013;doi: 10.1093/cid/cit394.

Brenseke, B., M.R. Prater, J. Bahamonde y J.C. Gutierrez. 2013. Current thoughts on maternal nutrition and fetal programming of the metabolic syndrome. Journal of Pregrancy. Vol. 2013, Article ID 368461, 13 páginas.


Díaz F, Donoso A, Carvajal C, Salomón T, Torres M, Erranz B, Cruces P. (2012) Consecuencias hemodinámicas y respiratorias iniciales del síndrome compartimental abdominal en un modelo experimental pediátrico. Revista Chilena Pediatría, 83(5): 454-461.

Díaz F, Erranz B, Donoso A, Carvajal C, Salomón T, Torres M, Cruces P. (2012) Surfactant deactivation in a paediatric model induces hypovolemia and fluid shift to the extravascular lung compartment. Pediatric Anesthesia, 23(3):250-7.

Díaz, F., Donoso, A., Carvajal, C., Salomón, T., Torres, M., Erranz, B., & Cruces, P. (2012). Veno-arterial difference of carbondioxide as a predictor of low cardiac output in an experimental pediatric model. Revista médica de Chile, 140(1):39–44.

Cruces P, Diaz F, Puga A, Erranz B, Donoso A, Carvajal C, et al. Angiotensin-converting enzyme insertion/deletion polymorphism is associated with severe hypoxemia in pediatric ARDS. Intensive Care Medicine. 2012 Jan;38(1):113-9. PubMed PMID: WOS:000297839600017.

Ezquer ME, Ezquer FE, Arango-Rodriguez ML, Conget PA. MSC transplantation: a promising therapeutic strategy to manage the onset and progression of diabetic nephropathy. Biological Research. 2012 2012;45(3):289-96. PubMed PMID: WOS:000310478900010.

Ezquer F, Ezquer M, Contador D, Ricca M, Simon V and Conget P (2012) The antidiabetic effect of mesenchymal stem cells is unrelated to their trans-differentiation potential but to their capability to restore Th1/Th2 balance and to modify the pancreatic microenvironment. Stem Cells 30: 1664-1674

Martinez J, Leal G, Conget P. Nosema ceranae an emergent pathogen of Apis mellifera in Chile. Parasitology Research. 2012 Aug;111(2):601-7. PubMed PMID: WOS:000306694400013.

Martinez-Fong D, Bannon MJ, Trudeau L-E, Gonzalez-Barrios JA, Arango-Rodriguez ML, Hernandez-Chan NG, et al. NTS-Polyplex: a potential nanocarrier for neurotrophic therapy of Parkinson’s disease. Nanomedicine-Nanotechnology Biology and Medicine. 2012 Oct;8(7):1052-69. PubMed PMID: WOS:000309216300002.

Vaisman A, Espinosa M, Melean P, Gallegos M, Calvo C, Figueroa D and Conget P (2012) Steroids and platelet rich plasma as coadjuvants to microfracture for the treatment of chondral lesions in an animal model: can the healing be enhanced? Cartilage doi: 10.1177/1947603511422053

Rodriguez F, Gana MJ, Yubero MJ, Zillmann G, Kramer SM, Catalan J, Rubio-Astudillo J, Gonzalez S, Liu L, Ozoemena L, Mellerio J, McGrath JA, Palisson F and Conget P (2012) Novel and recurrent COL7A1 mutations in Chilean patients with dystrophic epidermolysis bullosa. J Dermatol Sci 65: 149-152


Cruces P, Ronco R, Erranz B, Conget P, Carvajal C, Donoso A and Diaz F. Mild hypothermia attenuates lung edema and plasma interleukin-1beta in a rat mechanical ventilation-induced lung injury model. Exp Lung Res 37: 549-554, 2011.

Castro EA, Millan D, Aguayo R, Campodonico PR and Santos J.G. Reaction of aryl acetates with secondary alicyclic amines in etanol/water mixtures: Effect of the solvent composition on the kinetic and mechanism. Int J Chem Kinetics 43: 687-693, 2011.

Encina G, Ezquer F, Conget P and Israel Y. Insulin is secreted upon glucose stimulation by both gastrointestinal and enteroendocrine K-cells and L-cells engineered with the prepoinsulin gene. Biol Res 44: 301-305, 2011.

Ezquer M, Ezquer F, Ricca M, Allers C and Conget P. Intravenous administration of multipotent stromal cells prevents the onset of non-alcoholic steatohepatitis in obese mice with metabolic syndrome.J Hepatol 55: 1112-1120, 2011.

Ezquer F, Ezquer M, Simon V and Conget P. The antidiabetic effect of MSCs is not impaired by insulin prophylaxis and is not improved by a second dose of cells. PLoS ONE 6: e16566, 2011.

Illanes S, Liesz A, Sun L, Dalpke A, Zorn M and Vetkamp R. Hematoma size as major modulator of the cellular immune system after experimental intrecerebral hemorrhage. Neurosc Lett 490: 170-174, 2011.

Ormazábal-Toledo R, Campodónico PR and Contreras R.Are electrophilicity and electrofugality related concepts? A density functional theory study.Org Lett 13: 822-824, 2011.


Campodónico PR, Ormazábal-Toledo R. Aizman A and Contreras R. Permanent group effect on nucleofugality in aryl benzoates. Chem Phys Lett 498: 221–225, 2010.

Somoza R, Juri C, Baes M, Wyneken U and Rubio FJ. Intranigral transplantation of epigenetically induced BDNF-secreting human mesenchymal stem cells: implication for cell-based therapies in Parkinson’s disease. Biol Blood Marrow Transpl 16: 1530-1540, 2010.

Martínez J, Simon V, Gonzalez B and Conget P. A real-time PCR-based strategy for the detection of Paenibacillus larvae vegetative cells and spores to improve the diagnosis and the screening of American foulbrood. Lett Appl Microbiol 50: 603-610, 2010.

Valle-Prieto A and Conget PA. Human mesenchymal stem cells efficiently manage oxidative stress. Stem Cells Dev 19: 1885-1893, 2010.

Manigold T, Mori A, Graumann R, Llop E, Pilcher H, Simon V, Valdivieso F, Castillo C, Hjelle B and Vial P. Highly differentiated, resting Gn–specific memory CD8+ T Cells persist years alter infection by Andes Hantavirus. PLoS Pathog 6: e1000779, 2010.

Campodónico PR, Aliaga M, Santos J, Castro E and Contreras R. Reactivity of benzohydrazide derivatives towards acetylation reaction. Experimental and theoretical studies. Chem Phys Lett 488: 86-89, 2010.

Conget P, Rodriguez F, Kramer S, Allers C, Simon V, Palisson F, Gonzalez S and Yubero MJ.Replenishment of type VII collagen and re-epithelialization of chronically ulcerated skin after intradermal administration of allogeneic mesenchymal stromal cells in two patients with recessive dystrophic epidermolysis bullosa. Cytotherapy 12: 429-431, 2010.

Conget P and Beca J. Creación de una célula artificial y sus implicancias. Bioética & Debat, Julio, 2010.

Urrutia J, Mery P, Martínez R, Pizarro F, Apablaza D, Mardones R. “Cultured autologous bone marrow stem cells inhibit bony fusion in a rabbit model of posterolateral lumbar fusion with autologous bone graft.” J Clin Neurosci. 2010 Apr;17(4):481-5.

Gonzalez M, Martínez R, Amador C, Michea L.  “Regulation of the sodium-phosphate cotransporter Pit-1 and its role in vascular calcification”. Curr Vasc Pharmacol. 2010 Jan 1.

Mardones R, Martínez R, Paredes MJ, Zalaquett E.  “Chondrogenic Differentiation of Bone Marrow Mesenchymal Stem Cells. First Successful Latin-American Report”. International Journal of  Morphology 28(3):749-754, 2010.


Castro E, Aliaga M, Campodónico PR, Cepeda M, Contreras R and Santos J. Experimental and theoretical studies on the nucleofugality patterns in the aminolysis and phenolysis of S-Aryl Thiocarbonates. Chem Phys Lett 74: 9173-9179, 2009.

Ezquer F, Ezquer M, Simón V, Pardo F, Yáñez A, Carpio D, and Conget P. Endovenous administration of Bone Marrow-Derived Multipotent Mesenchymal stromall Cells pevents Renal Failure in Diabetic Mice. Biol Blood Marrow Transplant 15:1354-1365, 2009.

Browne EP, Allers C and Landau N. Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent. Virology 387: 313-321, 2009.

Campodónico PR, Aizman A and Contrera R. Electrophilicity of quinones and its relationship with hydride affinity. Chem Phys Lett 471: 168-173, 2009.

Medina R, Torres-Perez F, Galeno H, Navarrete M, Vial PA, Palma RE, Ferres M, Cook JA and Hjelle B. Ecology, genetic diversity, and phylogeographic structure of Andes virus in humans and rodents in Chile. J Virol 83: 2446-2459, 2009.

Bertrán K, Donoso A, Cruces P, Díaz F and Arraigada D. Asplenia congénita y púrpura fulminans neumocóccico en paciente pediátricoReporte de caso con necropsia y revisión del tema.  Rev Chil Infect, 26: 55-59, 2009.

R. Martínez, R. Mardones.  “Stem Cell based Therapy in Chile – From de lab to the Patients”.  Cartilage, August 2009; vol. 1, 1 suppl: pp. 1S-63S.


Campodónico PR, Andrés J, Aizman A and Contreras R. Proton-transport catalysis in intramolecular rearrangements: A density functional theory study.Chem Phys Lett 464: 271-275, 2008.

Manigold T, Martinez J, Lazcano X, Ye C, Schwartz S, Cuiza A, Valdivieso F, Hjelle B, and Vial P. Case report: T-Cell responses during clearance of Andes virus from blood cells 2 months after severe Hantavirus cardiopulmonary syndrome.J Med Virol 80: 1947-1951, 2008.

Reyes LI, León F, González P, Rozas MF, Labarca C, Segovia A, Neira O and Naves R. Dexamethasone inhibits BAFF expression in fibroblast-like synoviocytes from patients with rheumatoid arthritis. Cytokine 42: 170-178, 2008.

Ezquer M, Valdez R, Seltzer A and Jahn G. Advancement of reproductive senescence and changes in the early expression of oestrogen, progesterone and µ-opioid receptors induced by neonatal hypoxia in the female rat. Brain Res 1214: 73-83, 2008.

Somoza R, Conget P and Rubio F. Neuropotency of human mesenchymal stem cell cultures : clonal studies reveal the contribution of cell plasticity and cell contamination.Biol Blood Marrow Transplant 14: 546-555, 2008.

Ezquer F, Ezquer M, Parraut D, Carpio D, Yañez A and Conget P. Systemic administration of multipotent mesenchymal stromal cells reverts hypergycemia and prevents nephropathy in type 1 diabetic mice. Biol Blood Marrow Transplant 14: 631-640, 2008.

Campodónico PRand Contreras R. Structure-reactivity relationships for electrophilic sugars in interaction with nucleophilic biological targets. Bioorg Med Chem 16: 3184-3190, 2008.

Castro E, Aliaga M, Campodónico PR, Leis J, García-Río L and Santos J. Reactions of aryl chlorothionoformates with quinuclidines. A kinetic study.J Phys Org Chem 21: 102 -107, 2008.

Donoso A, Cruces P, Díaz F and Clavería C. Shock cardiogénico causado por implantación anómala de arteria coronaria.  Rev Chil Pediatr, 79: 509-515, 2008.

Donoso A, Díaz F, Bertrán K  and  Cruces P. Pericarditis purulenta primaria por Streptococcus pneumoniae, a propósito de un caso clínico. Rev Chil Pediatr, 79: 623-628, 2008.

Tobias Manigold, Jessica Martínez, Sheina Schwartz, Andres Mori, Rebecca Graumann, Analía Cuiza, Francisca Valdivieso, Brian Hjelle, Pablo Vial (2008) Case Report: T-cell associated clearance of persistent Andes hantavirus in peripheral blood cells from a survivor of severe Hantavirus Cardiopulmonary Syndrome. Journal of Medical Virology 80:1947-1951.