Dr. med. Thomas Weitzel DTM&P

·         Profesor Titular, Facultad de Medicina Clínica Alemana, Universidad del Desarrollo

·         Investigador, ICIM – Programa Hantavirus y Zoonosis, Chilean Rickettsia and Zoonosis Research Group, Laboratorio Clínico –  Clínica Alemana

·         Jefe Programa Medicina del Viajero, Clínica Alemana de Santiago

·         ORCID ID: https://orcid.org/0000-0002-9804-2123

 

Médico Cirujano y Doctorado en Medicina, Universidad de Kiel (Alemania). Entrenamiento Hospital St. Georg, Hamburgo, y Charité, Berlín, Alemania. Microbiólogo (Hamburgo, Alemania), Internista (Berlín, Alemania), subespecialista en enfermedades infecciosas y en medicina tropical (Berlín, Alemania), diploma de medicina tropical y parasitología (DTM&P), Instituto Bernhard-Nocht (Hamburgo, Alemania).

Líneas de investigación e intereses: Enfermedades trasmitidas por vectores, zoonoses, rickettsias, enfermedades tropicales e importadas, parasitosis

 

Dr. Thomas Weitzel is a clinical microbiologist and infectious diseases physician specialized in Tropical and Travel Medicine. After obtaining his medical degree from Kiel University, Germany, he completed his specialization in Clinical Microbiology, Internal Medicine, Infectious Diseases, and Tropical Medicine in Hamburg and Berlin, Germany. From 2000 to 2009, he worked at the Charité Berlin, where he was Head of the Diagnostic Laboratory and parasitology lecturer at the Institute of Tropical Medicine and International Health. Since 2009 he works in Santiago, Chile, as a Tropical Medicine specialist and Head of the Travel Medicine Program at Clínica Alemana. He is teaching and performing research at the Medical Faculty of Universidad del Desarrollo, where he was appointed Full Professor in 2015. His main research interests are zoonotic and vector-borne infections as well as other tropical and travel-related diseases. He is co-founder of the Chilean Rickettsia and Zoonosis Research Group, exploring the field of emerging rickettsial infections in Chile. Up to date, he has published >80 papers in peer-reviewed journals and >20 book chapter and contributes to several journals in editorial functions.

 

Publicaciones internacionales seleccionadas

Zoonosis / Enfermedades trasmitidas por vectores

Weitzel T, Acosta-Jamett G, Jiang J, Martínez-Valdebenito C, Farris CM, Richards AL, Abarca K. Human seroepidemiology of Rickettsia and Orientia species in Chile – a cross-sectional study in five regions. Ticks Tick Borne Dis 2020; 11: 101503

Abarca K, Martínez-Valdebenito C, Angulo J, Jiang J, Farris CM, Richards AL, Acosta-Jamett G, Weitzel T. Molecular description of a novel Orientia species causing scrub typhus in Chile. Emerg Infect Dis 2020 Sep. doi: 10.3201/eid2609.200918

Weitzel T, Makepeace BL, Elliott I, Chaisiri K, Richards AL, Newton PN. Marginalised mites – neglected vectors of neglected diseases. PLOS Negl Trop Dis 2020; 14: e0008297

Acosta-Jametta G, Weitzel T, López J, Alvarado D, Abarca K. Prevalence and risk factors of antibodies to Anaplasma spp. in Chile – a household-based cross-sectional study in healthy adults and domestic dogs. Vectors Borne Zoonotic Dis 2020; doi: 10.1089/vbz.2019.258

Acosta-Jamett G, Martínez-Valdebenito C, Beltrami E, Silva-de la Fuente MC, Jiang J, Richards AL, Weitzel T, Abarca K. Identification of trombiculid mites (Acari: Trombiculidae) on rodents captured on Chiloé Island and molecular evidence of infection with Orientia species. PLOS Negl Trop Dis 2020; 14: e0007619

Weitzel T, Acosta-Jamett G, Martínez-Valdebenito, Richards AL, Grobusch MP, Abarca K. Scrub typhus risk in travelers to southern Chile. Travel Med Infect Dis 2019; 29: 78-9

Weitzel T, Martínez-Valdebenito C, Acosta-Jamett G, Jiang J, Richards AL, Abarca K. Scrub typhus in continental Chile, 2016-2018. Emerg Infect Dis 2019; 25: 1214-7

Weitzel T, Aylwin M, Martínez-Valdebenito C, Jiang J, Munita JM, Thompson L, Abarca K, Richards AL. Imported scrub typhus: first case in South America and review of the literature. Trop Dis Travel Med Vaccines 2018; 4:10

Weitzel T, Jiang J, Acosta-Jamett G, Martínez-Valdebenito C, López J, Richards AL, Abarca K. Canine seroprevalence to Orientia species in southern Chile: A cross-sectional survey on the Chiloé Island. PLOS One 2018; 13: e0200362

Díaz F, Martínez-Valdebenito C, López J, Weitzel T, Abarca K. Geographical distribution and phylogenetic analysis of Rhipicephalus sanguineus sensu lato in northern and central Chile. Ticks Tick Borne Dis 2018; 9:792-7

Weitzel T, López J, Acosta-Jamett G, Edouard S, Parola P, Abarca K. Absence of convincing evidence of Coxiella burnetii infection in Chile: a cross-sectional serosurvey among healthy adults in four different regions. BMC Infect Dis 2016; 16: 541

Weitzel T, López J, Dittrich S, Phuklia W, Velásquez K, Blacksell SD, Paris D, Abarca K. Endemic scrub typhus in South America. New Engl J Med 2016; 375: 954-61

Acosta-Jamett G*, Weitzel T, Gadones C, Bahamonde A, Abarca K, Reiter-Owona I. Prevalence and risk factors for human and canine echinococcal infection in a rural area of Northern Chile: a household-based cross-sectional study. PLOS Negl Trop Dis 2014; 8: e3090

 

Medicina del Viajero / Infecciones importadas

Weitzel T. Profile and complexity of travel medicine consultations in Chile: unicentric cross-sectional study. BMJ Open 2020 (en prensa)

Rothe C, Boecken G, Rosenbusch D, Alberer M, Buhler S, Burchard G, Erkens K,  Feldt T, Grobusch MP, Köhler C, Löbermann M, Meischner K, Metzger W, Muller A, Nothdurft HD, Rieke B, Schlaich C, Schönfeld C, Schulze MH, Siedenburg J, Steiner F, Weitzel T, Veit O. Recommendations for antimalarial prophylaxis. Flugmed Tropenmed Reisemed 2019; 26: 105-32; doi: 10.1055/a-0916-5128

Weitzel T, Vial P, Perret C, Aguilera X. Shortage of yellow fever vaccination: a Travel Medicine emergency for Chilean travelers. Travel Med Infect Dis 2019; 28:1-2

Grobusch MP, Schaumburg F, Weitzel T, Rothe C, Hanscheid T, Goorhuis A. Ebola 2018 – Implications for travel health advice and relevance for travel medicine. Travel Med Infect Dis 2018; 24: 1-3

Weitzel T, Soto A, Sánchez M, Larrondo J. Chronic skin ulcers in a patient returning from Mexico. Lancet Infect Dis 2016; 16: 264

Weitzel T, Labarca J, Cortes CP, Rosas R, Balcells ME, Perret C. Cluster of imported vivax malaria in travelers returning from Peru. J Travel Med 2015; 22: 415-8

Weitzel T, Rolling T, Burchard GD, Cramer JP. Malaria prophylaxis in Latin America – a controversial topic. Am J Trop Med Hyg 2012, 87:190-1

Weitzel T, Schnabel E, Dieckmann S, Schweiger B. Evaluation of a new point-of-care test for influenza A and B in travelers with flu-like symptoms. Clin Microbiol Infect 2007, 13: 665-9

Weitzel T, Wichmann O, Mühlberger N, Reuter B, Hoof HD, Jelinek T. Clinical and epidemio-logical features of travel-associated cryptosporidiosis. Clin Microbiol Infect 2006; 12: 921-4

Rack J, Wichmann O, Kamara B, Günther M, Cramer J, Schönfeld C, Henning T, Schwarz U, Mühlen M, Weitzel T, Friedrich-Jänicke B, Foroutan B, Jelinek T. Risk and spectrum of diseases in travelers to popular tourist destinations. J Travel Med 2005; 12: 248-53

Weitzel T, Mühlberger N, Jelinek T, Schunk M, Ehrhardt S, Bogdan C, Arasteh K,  Schneider T, Kern WV, Fätkenheuer G, Boecken G, Zoller T, Probst M, Peters M, Weinke T, Gfrörer S, Klinker H, Holthoff-Stich ML for SIMPID Surveillance Network. Imported leishmaniasis in Germany 2001-2004: data of the SIMPID surveillance network. Eur J Clin Microbiol Infect Dis 2005 ; 24: 471-6

Mühlberger N, Jelinek T, Behrens R, Coulaud JP, Clerinx J, Gjørup I, Puente S, Burchard G, Corachán M, Grobusch MP, Weitzel T, Zoller T, Kollaritsch H, Beran J, Iversen J, Hatz C, Schmid M, Björkmann A, Fleischer K, Bisoffi Z, Guggemos W, Knobloch J, Matteelli A, Schulze MH, Laferl H, Kapaun A, McWhinney P, Lopez-Velez R, Fätkenheuer G, Kern P, Zieger BW, Kotlowski A, Fry G, Cuadros J, Myrvang B – for TropNetEurop and SIMPID Surveillance Networks. Age is a Risk Factor for Severe Manifestations and Fatal Outcome in European Patients with Falciparum Malaria: Observations from TropNetEurop- and SIMPID-Surveillance Data. Clin Infect Dis 2003; 36: 990-5

 

Parasitología

Weitzel T, Cabrera J, Rosas R, Noriega LM, Schiapacasse G, Vollrath V, Porte L. Enteric multiplex PCR panels: A new diagnostic tool for amebic liver abscess? New Microbes New Infect 2017; 18: 50-3

Weitzel T, Rosas R, Fica A, Dabanch J, Polanco M, Egaña A, Triantafilo V, Pfaff K, Hoerauf A, Reiter-Owona I. Is there a risk of filarial infection during long-term missions in Haiti? Travel Med Infect Dis 2016; 14: 137-42  

Weitzel T, Yamasaki H, Sugiyama H, Ramirez C, Rosas R, Mercado R. Human Infections with Pseudoterranova cattani Nematodes, Chile. Emerg Infect Dis 2015; 12: 1874-5

Broglia A, Weitzel T, Harms G, Cacció SM, Nöckler K. Molecular typing of Giardia duodenalis isolates from German travellers. Parasitol Res 2013, 112: 3449-56

Kinkel HF, Dittrich S, Bäumer B, Weitzel T. Evaluation of eight serological tests for diagnosis of imported schistosomiasis. Clin Vaccin Immunol 2012, 19: 948-53

Weitzel T, Zulantay I, Danquah I, Hamann L, Apt W, Mockenhaupt FP. Mannose-binding lectin and toll-like receptor polymorphisms and Chagas disease in Chile. Am J Trop Med Hyg 2012; 86: 229-32

Fica A, Dabanch J, Farias C, Castro M, Jercic MI, Weitzel T. Acute fascioliasis – clinical and epidemiological features of four patients in Chile. Clin Microbiol Infect 2012; 18: 91-6

Weitzel T, Jelinek T. Images in clinical medicine. Loiasis. N Engl J Med 2006; 355:e6

Weitzel T, Dittrich S, Möhl I, Adusu E, Jelinek T. Evaluation of seven commercial antigen detection tests for Giardia and Cryptosporidium in stool samples. Clin Microbiol Infect 2006; 12: 656-9

Weitzel T, Wolff M, Dabanch J, Levy I, Schmetz C, Visvesvara GS, Sobottka I. Dual microsporidial infection with Encephalitozoon cuniculi and Enterocytozoon bieneusi in an HIV-positive patient. Infection 2001; 29: 237-9

 

Otros

Porte L, Legarraga P, Vollrath V, Aguilera X, Munita JM, Araos R, Pizarro G, Vial P, Dittrich S, Weitzel T. Evaluation of novel antigen-based rapid detection test for the diagnosis of SARS-CoV-2 in respiratory samples. Int J Infect Dis 2020; doi: 10.1016/j.ijid.2020.05.098.

Weitzel T, Rodríguez F, Noriega LM, Marcotti A, Duran L, Palavecino C, Porte L, Aguilera X, Wolff M, Cortes CP. Hepatitis B and C virus infection among HIV patients within the public and private healthcare systems in Chile: a cross-sectional serosurvey. PLOS ONE 2020; 15: e0227776

Porte L, Valdivieso F, Wilmes D, Gaete P, Díaz C, Thompson L, Munita JM, Alliende R, Varela C, Rickerts V, Weitzel T. Laboratory exposure to Coccidioides: lessons learnt in a non-endemic country. J Hosp Infect 2019; 102: 461-4

Porte L, García P, Braun S, Ulloa MT, Lafourcade M, Montaña A, Miranda C, Weitzel T. Head-to-head comparison of Microflex LT and Vitek MS systems for routine identification of microorganisms by MALDI-TOF mass spectrometry in Chile. PLOS One 2017; 12: e017792

Porte L, Varela C, Haecker T, Morales S, Weitzel T. Impact of changing from staining to culture techniques on detection rates of Campylobacter spp. in routine stool samples in Chile. BMC Infect Dis 2016; 16: 196

Salvador F, Porte L, Duran L, Marcotti A, Pérez J, Thompson L, Noriega LM, Lois V, Weitzel T. Breakthrough bacteremia due to Clostridium tertium in a patient with neutropenic fever and identification by MALDI-TOF mass spectrometry. Int J Infect Dis 2013, 17: e1062-3

Otto-Knapp R, Cortes CP, Saavedra F, Wolff M, Weitzel T. Hepatitis B prevalence and influence on HIV treatment outcome and mortality in the Chilean AIDS cohort. Int J Infect Dis 2013, 17: e919-24

Weitzel T, Reither K, Mockenhaupt FP, Stark K, Ignatius R, Saad E, Seidu-Korkor A, Bienzle U, Schreier E. Field evaluation of a rota- and adenovirus immunochromatographic assay using stool samples from children with acute diarrhea in Ghana. J Clin Microbiol 2007; 45: 2695-7

 

Capitulos de libros selectionados

El Dib NA, Weitzel T. Microsporidiosis. In: Bruschi F. (ed.). Frontiers in Parasitology (Vol. #2) – Water-borne Protozoa in Humans, Bentham Science Publishers, Sharjah, United Arab Emirates, 2017; p. 221-75. ISBN 9781681084343

Weitzel T. Impfungen bei HIV-Patienten. In: Hoffmann C, Rockstroh JK, (eds.). HIV 2016/2017, Medizin Fokus Verlag, Hamburg, 2016; p. 461-9. ISBN: 9783941727205

Weitzel T. HIV und Reisen. In: Hoffmann C, Rockstroh JK, (eds.). HIV 2016/2017, Medizin Fokus Verlag, Hamburg 2016; p. 470-6. ISBN: 9783941727205

Weitzel T. Traveling with HIV.  In: Hoffmann C, Rockstroh JK, (eds.). HIV 2015/2016, Medizin Fokus Verlag, Hamburg, 2015; p. 506-12. ISBN: 9783941727175

Weitzel T. Vaccinations and HIV. In: Hoffmann C, Rockstroh JK, (eds.). HIV 2015/2016, Medizin Fokus Verlag, Hamburg, 2015, p. 494-505. ISBN: 9783941727175

Weitzel T. A 4-year-old girl from Bolivia with a dark nodule on her toe. In: Rothe C (ed.). Clinical Cases in Tropical Medicine, Elseview, London, 2014; p. 251-2. ISBN: 9780702058240

Weitzel T , El-Dib N. A 25-year-old woman from Egypt with severe chronic diarrhea and malabsorption. In: Rothe C (ed.). Clinical Cases in Tropical Medicine, Elseview, London, 2014; p. 228-30. ISBN: 9780702058240

Neira P, Weitzel T, Mehlhorn H. Chapter 23: Cryptosporidiasis. In: Apt W (ed.). Parasitología Humana, McGraw-Hill, New York, 2013; p. 167-74. ISBN: 9786071508768

Weitzel T, Neira P, Mehlhorn H. Chapter 24: Ciclosporiasis. In: Apt W (ed.). Parasitología Humana, McGraw-Hill, New York, 2013; p. 175-8. ISBN: 9786071508768

El-Dib N, Weitzel T. Chapter 36: Capilariasis intestinal. In: Apt W (ed.). Parasitología Humana, McGraw-Hill, New York 2013; p. 250-5. ISBN: 9786071508768

El-Dib N, Weitzel T. Chapter 62: Capilariasis tisulares. In: Apt W (ed.). Parasitología Humana, McGraw-Hill, New York 2013; p. 481-4. ISBN: 9786071508768